Any Level 1 evidence of efficacy?Updated 6 months ago

No. Level 1 evidence of efficacy indicates a systematic review and meta-analysis of randomized, controlled trials. This is generally only found among older drugs and some supplements that have been on the market long enough to compile enough data to make a systematic review and meta-analysis not only possible, but necessary. New drugs and supplements will not have Level 1 evidence. Daily Microbiome Nutrition was developed using the best available evidence, which includes ingredient specific RCTs in humans to establish therapeutic doses for some ingredients and varied levels of evidence for the others.